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title: Gattefosse_CP_BrandedContent_0126_LandingPage
description: In this whitepaper, Gattefossé Pharmaceuticals seeks to bridge the gap between lipid-based formulations and oral solid dosage forms, demonstrating the utility and potential of incorporating lipid excipients into modern OSD development.
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# Exclusive Whitepaper from Gattefossé

![928627237658790___260116BeyondtheCapsulePrimaryImage840x454](https://lp.contractpharma.com/hs-fs/hubfs/928627237658790___260116BeyondtheCapsulePrimaryImage840x454.jpg?width=840&height=454&name=928627237658790___260116BeyondtheCapsulePrimaryImage840x454.jpg "928627237658790___260116BeyondtheCapsulePrimaryImage840x454")

# Beyond the Capsule: Unlocking the Full Potential of Lipid Excipients in Oral Solid Dosage Forms

Modern drug discovery is increasingly plagued by both poor solubility and limited permeability. While lipid-based formulations have long been recognized as the gold standard for overcoming bioavailability hurdles, they have traditionally been confined to capsule technologies.

**In this whitepaper, Gattefossé Pharmaceuticals seeks to bridge the gap between lipid-based formulations and oral solid dosage forms, demonstrating the utility and potential of incorporating lipid excipients into modern OSD development.**

Inside, you will find:

- **The Power of Solid Lipids:** Learn how Compritol® 888 ATO solves critical OSD challenges, including tablet lubrication, taste-masking, and creating sustained-release matrices that can reduce tablet volume by up to 60%.
- **Lipid-Polymer Synergies:** Explore how ternary Amorphous Solid Dispersions (ASDs) using Gelucire® and Labrasol® ALF enable stable drug loading, increase in vivo exposure by up to 1.7-fold, and enhance dissolution by 4.5-fold.
- **Solidified Solubilizers (Solid SEDDS):** Discover the technique of adsorbing liquid SEDDS onto porous carriers to create free-flowing, compressible powders that retain the powerful benefits of liquid formulations.

Novel APIs require innovative solutions. Download the whitepaper below and learn how established lipid chemistries offer a safe, scalable approach to accelerate your next tablet formulation to market.

# Gattefossé

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